Neuroinfectious Disease - Current Fellows and Alumni

Current Fellow

Dr. Temesgen Nurye
Post-Doctoral Clinical Research Fellow (2023-2024)

 

Temesgen Nurye, MD

Temesgen Nurye, MD

My Name is Temesgen Nurye. I am an Assistant Professor of Neurology at Wollo University in Dessie, Ethiopia, and a Neurology specialist at Dessie Comprehensive Specialized Hospital under Wollo University. I recently completed a postgraduate program in Equity in Brain Health at the University of California, San Francisco. This program provided me with an exceptional opportunity to deepen my understanding of cutting-edge scientific research and advancements in neurodegenerative disorders.

I am now in a Neuroinfectious Disease research fellowship at Columbia University Irving Medical Center under the guidance and mentorship of Dr. Kiran Thakur. My primary research project has been focused on the implementation of current standards of care for screening, prevention, diagnosis, and treatment of cryptococcal meningitis (CM) in HIV-infected populations at two study sites in Ethiopia, Zewditu Memorial Hospital and Ayder Comprehensive Specialized Hospital. My responsibilities include 1) identifying study sites based on the burden of HIV cases and establishing research teams at both sites. 2) reviewing existing hospital infrastructure and gaps in the care of cryptococcal meningitis such as the availability of cryptococcal antigen (CrAg) screening, CD4 count testing, anti-fungal drugs for treatment of cryptococcal meningitis, and lumbar puncture (LP) kit, and 3) developing logistical and clinical workflows to improve the care of cryptococcal meningitis in people with HIV and increase the availability of resources such as CrAg test, CD4, and medications to meet the demands at the study sites. For this project, I am working closely with Dr. Thakur, research teams, and study coordinators on-site and leading the implementation project.

Alumni

Vivian Ssonko Namale (MBChB, MMED Pediatrics, Post-Doctoral Clinical Research Fellow (2019-2020))

Current Positions:

  1. Research Physician Bioscience Research, Sub-Investigator
  2. Board Member International League Against Epilepsy
  3. Board Member East African Child Neurology in charge of Research
  4. Lecturer Department of Child Neurology Makerere University

Current/ Completed activities following Fellowship:

  1. Completed Clinical research on Etiology of Bacterial Meningitis among Children in Uganda following grant from World Federation of Neurology
  2. Completed Book chapter published in Frontier Neurology Bacterial Meningitis in Africa.
  3. Currently preparing for symposium under the international Child Neurology Congress
  4. Training for management of childhood epilepsies.

Being a part of the fellowship set me on a path of research provided me a better understanding of the principles of a good research project and understanding of available opportunities in research. In Africa in general where most of the neurological ailments occur very little documentation is being done. Being a part of this fellowship allowed me to see the need and be part of the group working tirelessly to ensure proper documentation and overall improvement of patient care of my patients.

Dr. Mashina Chomba, Post-Doctoral Clinical Research Fellow (2020-2021)

Dr Mashina Chomba is a Consultant Neurologist and Faculty member in the department of Internal Medicine at the University of Zambia and University Teaching Hospital in Lusaka, Zambia and is one of Zambia's first locally trained neurologists. He is a passionate researcher and teacher and has been part of research efforts aimed at better understanding the epidemiology of neurological diseases, such as Neurocysticercosis and Neurosyphilis.

Dr Chomba is a graduate of the University of Zambia School of Medicine where he attained his medical degree and later his Master of Medicine degree in Neurology. He then completed a 1-year Columbia University Neuroinfectious Disease Post-Doctoral Clinical Research Fellowship in 2021. Through the collaborations formed during the fellowship, he went on to contribute to the World Health Organization 2021 Scientific Brief on NeuroCOVID and the clinical guidelines for management of encephalopathy in severe COVID-19. The skills acquired during the fellowship also served him well when he later completed an NIH Fogarty Global Health Fellow investigating the epidemiology of Neurocysticercosis in Zambia

His main hope is to contribute significantly to the understanding of the epidemiology of neurological disease in Sub-Saharan Africa; and to help formulate innovations that will improve the care of neurology patients in the region.

Dr. Biniyam A. Ayele, Post-Doctoral Clinical Research Fellow (2021-2022)

I had the privilege of training as a remote NeuroID fellow for the year 2021/2022 under supervision of Dr. Kiran Thakur at the prestigious Columbia University Irving Medical Center, USA. The training provides me a unique opportunity in understanding and addressing the complex challenges of neuroinfectious diseases and its impact on the wellbeing of our patients in Ethiopia. This transformative experience has had a profound impact on my clinical career, research endeavors, and professional aspirations. This immersive environment allowed me to broaden my understanding of the intricate connections between infectious agents and the central nervous system, particularly focusing on the HIV-associated cognitive impairments among HIV+ adults in Ethiopia.

During my fellowship, I had the privilege of working closely with Dr. Thakur, whose expertise and guidance were invaluable to my development as a clinician-scientist. Dr. Thakur's unwavering support and commitment to education inspired me to work on a training program which was funded by World Federation of Neurology (WFN) aimed at enhancing the knowledge and skills of our undergraduate medical students in performing lumbar punctures. In addition, the NeuroID training plays a crucial role in enhancing my research capacity and collaborative projects in the field of neuroinfectious diseases. Likewise, as part of the training, I had a unique opportunity to participate in the following projects: a) systematic review on Drug Resistance in TBM, b) Neurological Diagnoses in Hospitalized Patients During the B.1.1.529 Surge, and c) PICO review for the Meningitis roadmap.

Furthermore, the NeuroID training program at Columbia University has been instrumental in opening further training opportunities for me, as I am currently an Atlantic Fellow for Equity in Brain Health at the University of California San Francisco (UCSF). This fellowship will undoubtedly provide me with valuable experiences and insights in the field of brain health. Moreover, the training program at Columbia university has contributed to the advancement of my research career, as I have received a “Young Researcher Award” from the College of Health Science, Addis Ababa University in May 2023.

Finally, my training and collaboration with Dr. Kiran Thakur during my Post-Doctoral Research Fellowship in Neuroinfectious Diseases at Columbia University Irving Medical Center have been pivotal in shaping my clinical career, research skills, and professional goals.

Dr. Zomer Sardar, Post-Doctoral Clinical Research Fellow (2022-2023)

Dr. Zomer Sardar, a general neurologist from Pakistan, is presently practicing at a district-level hospital in Pakistan. She has also been working as a post-doctoral fellow in the neuroinfectious department of neurology at Columbia University Irving Medical Center in New York, USA since 2021.

During my remote fellowship in neuro-infectious diseases, I had the opportunity to work on several projects related to neurological diagnosis in COVID-19 patients, drug resistance in tuberculosis, and cryptococcal meningitis. Through this experience, I gained valuable research skills that will serve me well in my future studies. I also learned the importance of collaborating with other institutions and professionals in the field, as we worked with experts from various backgrounds to develop comprehensive approaches to tackling these diseases.

Aside from the practical skills and knowledge I gained, the fellowship also expanded my understanding of the impact of neuroinfectious diseases on individuals and communities. I was struck by the far-reaching consequences of these diseases, from the physical pain and suffering they cause to the economic and social impacts on affected individuals and their families.

Overall, my experience with Dr. Thakur and the other professionals involved in the fellowship has left me with a newfound appreciation for the importance of research and collaboration in addressing the complex challenges posed by neuroinfectious diseases. I am grateful for the opportunity to have participated in this program and look forward to applying the skills and knowledge I have gained in my future work.

Dr. Blen Mamo, Post-Doctoral Clinical Research Fellow (2023-2024)

Reflecting on my time as a post-doctoral neuroID clinical research fellow at CU in 2023/24, I am incredibly grateful for the opportunities and experiences I had. It provided an unparalleled platform for learning and contributing to the field of neuroinfectious diseases. One of the most rewarding aspects of my fellowship was the opportunity to deeply explore HIV and opportunistic infections in my home country. This firsthand exposure allowed me to gain a comprehensive understanding of the challenges faced by individuals living with these conditions and to contribute to developing effective interventions. My involvement in WHO and PAHO projects was another significant highlight of my fellowship. These projects enhanced my knowledge and provided invaluable insights into the epidemiology of neurological disease and the distribution of neuroinfectious diseases across various settings and age groups, emphasizing the devastating impact of neuroinfectious diseases on individuals and communities worldwide. Grant writing was a new experience for me, and I am grateful for the opportunity to learn and contribute to the development of a grant project focused on HIV-associated CNS cryptococcal infections. This process honed my skills in project design, budget planning, and scientific communication. Beyond these specific projects, my fellowship provided me with a strong foundation in all aspects of clinical research. I was exposed to different research areas which will undoubtedly serve me well in my future endeavors. The neuroID seminars and lectures were particularly stimulating, allowing me to engage with leading experts in the field and learn from their insights. The collaborative and supportive atmosphere created a conducive environment for intellectual growth and professional development. I also had the privilege of contributing to a section on vaccine-preventable diseases that was published in prestigious outlets such as Encephalitis International special publication and Psychology Today. This collaboration allowed me to advocate for the significance of vaccination in preventing neuroinfectious diseases. I am especially grateful for the mentorship and guidance of Dr. Kiran Thakur. Her tireless dedication, unwavering support, and exceptional leadership skills were instrumental in my success. I was fortunate to learn from her expertise and gain valuable insights into the nuances of clinical research. My passion for education and capacity building has been further ignited by my experiences during this fellowship. I am currently focused on developing and implementing capacity-building programs to empower healthcare professionals and communities to address the challenges posed by various neurological diseases. In conclusion, my year as a post-doctoral neuroID clinical research fellow at CU was a transformative experience. I am grateful for the opportunities, collaborations, and mentorship I received, which have equipped me with the knowledge, skills, and passion to make a meaningful impact in the field of neuroinfectious diseases.